AVHL, AVHR

Type: Interneuron
Connectivity:
- In MoW: AVH
- In WormWiring: AVHLh, AVHRh, AVHLm, AVHRm
- In Nemanode: AVH
In Wormbase: AVH, AVHL, AVHR
Lineage: AB alapaaaaa, AB alappapaa
Location: Lateral ganglia of head
Description: Unipolar ventral cord interneurons. The processes of each AVH neuron enter the nerve ring and cross the midline into the contralateral side. The processes then exit the nerve ring into the ventral cord where they extend to the preanal ganglion.
Neurotransmitter/ Neuropeptide:
Innexin expression:
- INX-1a
- INX-10a
- INX-12 (in early larva)
- UNC-9 (only in dauer)
(Altun et al., 2009; Bhattacharya et al., 2019)
Receptor expression:
- GLR-4; glutamate receptor subunit
- SER-2; tyramine receptor (a splice variant)
- Possibly GGR-1; GABA-A/glycine receptor-like protein
(Tsalik et al., 2003; Brockie et al., 2001; Fujiwara et al., 1996)
Function:
- Regulates touch-evoked escape response and motility (Chai et al., 2022)
Reporters:
- At CGC: OH16483 otIs768 [hlh-34p::GFP + unc-119(+)]
- Other:




 


 
 

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AVHL (AB alapaaaaa) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of AVHL (since last AVHL ancestor has not yet gone through its final division, the black sphere seen at the end of this movie is still AB alapaaaa); dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).

 
 

Click here for larger version
AVHR (AB alappapaa) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of AVHR (since last AVHR ancestor has not yet gone through its final division, the black sphere seen at the end of this movie is still AB alappapa); dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).


Last revision: August 7, 2024
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