AVJmainframe

  

AVJL, AVJR

Type: Interneuron
Connectivity:
- In MoW: AVJ
- In WormWiring: AVJL, AVJR, AVJLm, AVJRm
- In Nemanode: AVJ
In Wormbase: AVJ, AVJL, AVJR
Lineage: AB alapapppa, AB alapppppa
Location: Lateral ganglia of head
Description: Unipolar ventral cord interneurons. The processes of each AVJ neuron enter the nerve ring and cross the midline into the contralateral side. The processes then exit the nerve ring into the ventral cord where they extend to the preanal ganglion.
Neurotransmitter/ Neuropeptide:
While immunoreactive to anti-GABA, does not contain known genes for release of GABA
(Gendrel et al., 2016).
Innexin expression:
- CHE-7
- INX-1a
- INX-8
- INX-10a
- INX-12 (in early larva)
- INX-18
- UNC-7
- UNC-9 (only in dauer)
(Altun et al., 2009; Bhattacharya et al., 2019)
Receptor expression:
- GLR-1; glutamate receptor subunit
(Maricq et al., 1995)
Function:
Reporters:
- At CGC: KP987 nuIs1[glr-1p::GFP + glr-1(+) + lin-15(+)] X. Also expressed in AVG, DVC, PVC, PVQ, RIG, RIS, RMD, RMEL/R, SMD, URY (Hart et al., 1995).
- Others:





 
 

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AVJL (AB alapapppa) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of AVJL; dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).

 
 

Click here for larger version
AVJR (AB alapppppa) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of AVJR; dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).

Last revision: August 7, 2024
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