Type: Pharyngeal motor neuron
In MoW:
Male Wiring Project:
In Wormbase: M5
Lineage: MS paaapap
Location: Pharynx posterior bulb
Description: M5 is located subdorsally on the left, posterior to pm7. It sends one dorsal and one ventral process. Dorsal process makes a


half circle running behind pm7. The two processes then cross on the ventral side and run anteriorly adjacent to the ventral marginal cell until they reach the terminal bulb commissure. The processes pass under the cell bodies of motor neurons M2 and continue to meet in gap junctions on the dorsal side of the terminal bulb commissure. Along the way they also send short, posterior branches which run on either side of the subdorsal marginal cells (Albertson and Thomson, 1976)
Neurotransmitter/ Neuropeptide:
- Acetylcholine
- FLP-1; FMRFamide-like peptide
(Duerr et al., 2008; Nelson et al., 1998; Rand and Nonet, 1997-Appendix 2)
Innexin expression:
- UNC-9
(Altun et al., 2009)
Receptor expression:
- GLR-8; glutamate receptor subunit
(Brockie et al., 2001)
Function: Unknown or redundant (Avery and Thomas, 1997)

Click image for closeup view Click pictures for higher resolution images

See also Pharynx Atlas


Click here for larger version
M5 (MS paaapap) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of M5; dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).

Last revision: February 4, 2014