CANL, CANR

Type: Neuron with unknown function.
In MoW: CAN
Male Wiring Project: CANL, CANR
In Wormbase: CAN, CANL, CANR
Lineage: AB alapaaapa, AB alappappa
Location: Midbody, lateral sides
Description: Process runs along excretory canal, no chemical synapses seen, some gap junctions to excretory cells, essential for survival. Posterior processes terminate at the anus. After they are born, CAN neurons move some distance from the anterior end of the embryo to their final positions midway along the body
Neurotransmitter/ Neuropeptide:
- Monoamine; express VMaT, CAT-1
- NLP-10; neuropeptide-like protein
- NLP-15; neuropeptide-like protein
(Nathoo et al., 2001; Duerr et al., 1999)
Innexin expression:
- INX-3
- INX-7
- INX-12
- INX-13
- UNC-9
(Altun et al., 2009)
Receptor expression:
- SER-2; tyramine receptor (a splice variant)
- Possibly GGR-2; a GABA-A/glycine receptor-like protein
(Tsalik et al., 2003; Fujiwara et al., 1996)
Function: CANs are essential for survival.



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CANL (AB alapaaapa) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of CANL; dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).

 
 

Click here for larger version
CANR (AB alappappa) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of CANR; dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).

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