AUAL, AUAR

Type: Interneuron
Connectivity:
- In MoW: AUA
- WormWiring Project: AUALh, AUARh, AUALm, AUARm
- In Nemanode: AUA
In Wormbase: AUA, AUAL, AUAR
Lineage: AB alpppppppp, AB praaappppp
Location: Lateral ganglia of head
Description: Dendritic processes run with amphid neuron dendrites, but lack ciliated endings
Neurotransmitter/ Neuropeptide:
- Glutamate
(Lee et al., 1999)


Innexin expression:
- CHE-7
- INX-1a
- INX-1b
- INX-2
- INX-4
- INX-7
- INX-10a
- INX-14
- UNC-7
- UNC-9
(Altun et al., 2009; Bhattacharya et al., 2019)
Receptor expression:
- GLR-4; glutamate receptor subunit
- NPR-1; neuropeptide Y receptor like protein which mediates social feeding behavior
- SER-2; tyramine receptor (a splice variant)
- Possibly DOP-1; dopamine receptor
(Sanyal et al., 2004; Tsalik and Hobert, 2003; Coates and de Bono, 2002; Brockie et al., 2001)
Function:
- Regulates social feeding behavior along with AQR, PQR and URX neurons (Coates and de Bono, 2002)
- Regulates learned aversive behavior to pathogenic bacteria (Filipowicz et al., 2022)
- Mediates aversive response modulation in starvation conditions (Ezcurra et al., 2016)
Reporters:
- At CGC:
- Other:


Click image for closeup view Click pictures for higher resolution images
 
 

 
 

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AUAL (AB alpppppppp) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of AUAL; dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).

 
 

Click here for larger version
AUAR (AB praaappppp) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of AUAR; dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).


Last revision: July 19, 2024
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