Type: Interneuron
Connectivity:
- In MoW: AIN
- In WormWiring: AINL_h, AINR_h, AINL_m, AINR_m
- In Nemanode: AIN
In Wormbase: AIN, AINL, AINR
Lineage: AB alaaaalal, AB alaapaaar
Location: Lateral ganglia in the head
Description: Ring interneurons. The process of each AIN neuron enters the nerve ring subdorsally and after crossing the dorsal midline, runs round the nerve ring on the opposite side. After entering the ventral cord on the contralateral side, it ends within the ventral ganglion.
Neurotransmitter/ Neuropeptide:
- Acetylcholine
- FLP-19; FMRFamide-like peptide
(Although earlier reports suggested AIN might be glutamatergic, more recent studies showed it is not) (Pereira et al., 2015; Serrano-Saiz et al., 2013; Loer and Rand, 2022; Li and Kim, 2008; Lee et al., 1999).

Innexin expression:
- CHE-7
- INX-1a
- INX-1b
- INX-2 (plasticity in non-dauer)
- INX-8
- INX-10a
- INX-14
- INX-17
- INX-19 (only in dauer)
- UNC-7
- UNC-9
(Altun et al., 2009; Bhattacharya et al., 2019)
Receptor expression: Unknown
Function: Function in cold tolerance downstream of ASG (Takagaki et al., 2020).
Reporters:
- At CGC: OH16151 ynIs34 [flp-19p::GFP] IV. otEx7424 [lgc-35p::tagRFP + pha-1(+)]. Marked with both GFP &RFP.
- Other: