Literature Homepage

Literature on Aging in C. elegans

• Aging in the Nematode Caenorhabditis elegans: Major Biological and Environmental Factors Influencing Life Span
  Klass, M. 1977 Mech. Ageing Dev. 6: 413-29. doi: 10.1016/0047-6374(77)90043-4
  

• The Aging Process of the Nematode Caenorhabditis elegans in Bacterial and Axenic Culture
  Croll, N.A., Smith, J.M. and Zuckerman, B.M. 1977 Exp. Aging Res. 3: 175-189. doi: 10.1080/03610737708257101

• Age-dependent Changes in Mobility and Separation of the Nematode Caenorhabditis elegans
  Hosono, R., Sato, Y., Aizawa, S.I. and Mitsui, Y. 1980 Exp. Gerontol. 15: 285-9. doi: 10.1016/0531-5565(80)90032-7
  

• Quantitative Measures of Aging in the Nematode Caenorhabditis elegans. I. Population and Longitudinal Studies of Two Behavioral Parameters
  Bolanowski, M.A., Russell, R.L. and Jacobson, L.A. 1981 Mech. Ageing Dev. 15: 279-295 10.1016/0047-6374(81)90136-6

• The Autofluorescent "Lipofuscin Granules" in the Intestinal Cells of Caenorhabditis elegans are Secondary Lysosomes
  Clokey, G.V. and Jacobson, L.A. 1986 Mech. Ageing Dev. 1986 35: 79-94. doi: 10.1016/0047-6374(86)90068-0
  

• Stochastic and Genetic Factors Influence Tissue-specific Decline in Ageing C. elegans
  Herndon, L.A., Schmeissner, P.J., Dudaronek, J.M., Brown, P.A., Listner, K.M., Sakano, Y., Paupard, M.C., Hall, D.H. and Driscoll, M. 2002 Nature 419: 808-814 doi:10.1038/nature01135

• Genetic Analysis of Tissue Aging in Caenorhabditis elegans: a Role for Heat-shock Factor and Bacterial Proliferation
  Garigan, D., Hsu, A.L., Fraser, A.G., Kamath, R.S., Ahringer, J. and Kenyon, C. 2002 Genetics 161: 1101-12. doi: 10.1093/genetics/161.3.1101

• Behavioral Deficits During Early Stages of Aging in Caenorhabditis elegans Result from Locomotory Deficits Possibly Linked to Muscle Frailty
  Glenn, C.F., Chow, D.K., David, L., Cooke, C.A., Gami, M.S., Iser, W.B., Hanselman, K.B., Goldberg, I.G. and Wolkow, C.A. 2004 J. Gerontol. 59A: 1251-60. doi: 10.1093/gerona/59.12.1251
  

• Measurements of Age-related Changes of Physiological Processes that Predict Lifespan of Caenorhabditis elegans
  Huang, C., Xiong, C. and Kornfeld, K. 2004 Proc. Natl. Acad. Sci. USA 101: 8084-89. doi: 10.1073/pnas.0400848101

• Age-related Changes of Nuclear Architecture in Caenorhabditis elegans
  Haithcock, E., Dayani, Y., Neufeld, E., Zahand, A.J., Feinstein, N., Mattout, A., Gruenbaum, Y. and Liu, J. 2005 Proc. Natl. Acad. Sci. USA 102: 16690-95. doi: 10.1073/pnas.0506955102

• Quantitative Image Analysis Reveals Distinct Structural Transitions During Aging in Caenorhabditis elegans Tissues
  Johnston, J., Iser, W.B., Chow, D.K., Goldberg, I.G. and Wolkow, C.A. 2008 PLoS One 3: e2821. doi: 10.1371/journal.pone.0002821
  

• Loss of Intestinal Nuclei and Intestinal Integrity in Aging C. elegans
  McGee, M.D., Weber, D., Day, N., Vitelli, C., Crippen, D., Herndon, L.A., Hall, D.H. and Melov, S. 2011 Aging Cell 10: 699-710. doi: 10.1111/j.1474-9726.2011.00713.x

• Neurite Sprouting and Synapse Deterioration in the Aging Caenorhabditis elegans Nervous System
  Toth, M.L., Melentijevic, I., Shah, L., Bhatia, A., Lu, K., Talwar, A., Naji, H., Ibanez-Ventoso, C., Ghose, P., Jevince, A., Xue, J., Herndon, L.A., Bhanot, G., Rongo, C., Hall, D.H. and Driscoll, M. 2012 J. Neurosci. 32: 8778-90. doi: 10.1523/JNEUROSCI.1494-11.2012

• cep-1/p53-dependent Dysplastic Pathology of the Aging C. elegans Gonad
  McGee, M.D., Day, N., Graham, J. and Melov, S. 2012 Aging 4: 256-69. doi: 10.18632/aging.100448

• Extended Twilight among Isogenic C. elegans Causes a Disproportionate Scaling between Lifespan and Health
  Zhang, W.B., Sinha, D.B., Pittman, W.E., Hvatum, E., Stroustrup, N. and Pincus, Z. 2016 Cell Systems 3: 333-345.e4. doi: 10.1016/j.cels.2016.09.003
  

• Effects of Ageing on the Basic Biology and Anatomy of C. elegans
  Herndon, L.A., Wolkow, C.A., Driscoll, M. and Hall, D.H. 2017 In Ageing: Lessons from C. elegans. (ed Olsen, A. and Gill, M.) pp 9-39. doi: 10.1007/978-3-319-44703-2_2

• Mechanical Properties Measured by Atomic Force Microscopy Define Health Biomarkers in Ageing C. elegans
  Essmann C.L., Martinez-Martinez, D., Pryor, R., Leung, K.Y., Krishnan, K.B., Lui, P.P., Greene, N.D.E., Brown, A.E.X., Pawar, V.M., Srinivasan, M.A. and Cabreiro, F. 2020 Nature Comm. 11: 1043. doi: 10.1038/s41467-020-14785-0