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Putative sensory neuron
||Head; right hand side near the posterior bulb of pharynx.||Not known||None||DESCRIPTION|
Postembryonically born neuron with rudimentary cilium. AQR and its ciliated dendrite are directly exposed to the pseudocoelomic body fluid. AQR axonal process projects into ring.
Functions: Along with PQR, URX and AUA, AQR regulate social feeding (or aggregation on a bacterial lawn) and bordering (the accumulation of animals on the thickest part of a bacterial lawn) behavior since suppressing the activity of AQR, PQR, URX neurons inhibits social feeding (Coates J. C. and de Bono M., 2002). AQR, PQR and URX function as sensors of environmental oxygen which is a quantitative regulator of social feeding (Gray J. M. et al, 2004). Decreases in oxygen leads to a dose-dependent suppression of social feeding behavior and bordering. Oxygen acts in parallel to NPR-1 in regulating social feeding behavior.
Receptor expression: Expresses orphan receptor (chemosensory/odorant?) guanylyl cyclase, GCY-32 (Yu S. et al, 1997). Express neuropeptide Y receptor like protein, NPR-1 which mediates social feeding behavior (Coates J. C. and de Bono M., 2002). Express specific soluble guanylate cyclase homologue, GCY-35 which binds molecular oxygen and mediates oxygen sensation (Gray J. M. et al, 2004).
See gcy-32::GFP expression in AQR (Yu S. et al, 1997)