Type: Interneuron, sensory neuron (minor oxygen-sensory)
In MoW: SDQ
Male Wiring Project: SDQL, SDQR
In Wormbase: SDQ, SDQL, SDQR
Lineage: QL.pap, QR.pap
Location: SDQL in the anterior body, SDQR in the posterior body
Description: Postembryonic neurons, born in mid L1 stage
Neurotransmitter/ Neuropeptide:
- Acetylcholine
(Loer, 2010; Duerr et al, 2008; Rand and Nonet, 1997-Appendix 2)
Innexin expression:
- INX-7
- UNC-7
- UNC-9
(Altun et al., 2009)
Receptor expression:
Function:
- Soluble guanylate cyclase (sGC, e.g. GCY-35 and GCY-36)-expressing oxygen-sensing neurons (URX, AQR, PQR, SDQ, BDU, ALN, and PLN) mediate the avoidance of high O₂ levels (Zimmer et al, 2009). URX appears to be the most important member of this group, since its activity is uniquely important for aggregation (Coates and de Bono, 2002), while for aerotactic behavior in an O₂ gradient, URX is redundant with other sGC-expressing neurons (Chang et al., 2006).