RMGL, RMGR

Type: Interneuron
In MoW: RMG
Male Wiring Project:
RMGL, RMGR
In Wormbase: RMG, RMGL, RMGR
Lineage: AB plapaaapp, AB prapaaapp
Location: Head
Description: RMG neurons innervate muscles in the head via NMJs in the nerve ring
Neurotransmitter/ Neuropeptide:
- PDF-1; pigment dispensing factor homolog
(Barrios et al, 2012)
Innexin expression:
- UNC-7
(Altun et al., 2009)
Receptor expression:
Function:
- Functions as the center of a hub-and-spoke circuit, which works bidirectionally due to gap junctions, for pheromone attraction and social behavior. RMG is suggested to integrate signals from various sensory neurons, and, in turn, set the activity state for these neurons, modulating their chemosensory responses (Macosco et al., 2009; Lockery, 2009).


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RMGL (AB plapaaapp) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of RMGL; dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).

 
 

Click here for larger version
RMGR (AB prapaaapp) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of RMGR; dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).


Last revision: July 22, 2014
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