OLL

OLLL, OLLR

Type: Sensory neuron (mechanosensory)
In MoW: OLL
Male Wiring Project: OLLL OLLR
In Wormbase: OLL, OLLL, OLLR
Lineage: AB alppppapaa, AB praaapapaa
Location: Head
Description: Neurons of outer labial lateral sensilla, ciliated endings with striated rootlets. Sister cells of OLL neurons undergo apoptosis.
Neurotransmitter/Neuropeptide:
- Glutamate
(Pereira et al., 2015)
Innexin expression:
- UNC-7
- UNC-9
(Altun et al., 2009)
Receptor expression:
- PDFR-1; pigment dispersing factor (PDF-1) receptor
- SER-2 a splice variant of the tyramine receptor
(Barrios et al., 2012; Tsalik et al., 2003)
Function:
- Similar to ADE, PDE, CEP, FLP, IL1, OLQ neurons, OLL neurons have been connected to mechanosensation (Inglis et al., 2007)
- OLL neurons negatively regulate pathogen avoidance as laser ablation of these neurons leads to enhanced pathogen-avoidance behavior (Chang et al., 2011)

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Embryonic development of OLL neurons

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OLLL (AB alppppapaa) development in the embryo. Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of OLLL (since last OLLL ancestor has not yet gone through its final division, the black sphere seen at the end of this movie is still AB alppppapa); dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).

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OLLR (AB praaapapaa) development in the embryo. Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of OLLR (since last OLLR ancestor has not yet gone through its final division, the black sphere seen at the end of this movie is still AB paaapapa); dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).

OLL Sensory Endings

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3D reconstruction of the anterior sensory endings (cilia and dendrites) from high resolution serial section transmission electron micrographs. Bar 1 μm. Color code for the sensory endings is shown on the right-colors do not follow the WA color code. To expand, double click on the video, to return to original size, click "esc" (Doroquez et al., 2014)

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3D reconstruction of all amphid neuron cilia and associated socket and sheath cell processes. Modeled from serial section transmission electron micrographs (ssTEMs). Bar 1 μm. Color code for the sensory endings is shown on the left-colors do not follow the WA color code. To expand, double click on the video, to return to original size, click "esc" (Doroquez et al., 2014)

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3D reconstruction of IL1, IL2, OLL, OLQ and CEP sensory endings and associated glia. Colors do not follow the WA color code (purple; transition zone (TZ), lavender; CEP, blue; OLL and OLQ, beige; IL1, green; IL2, light pink; ILsh, dark pink; ILso, dark orange; OLso, light orange; OLsh, dark green; CEPso, light green; CEPsh).To expand, double click on the video, to return to original size, click "esc" (Doroquez et al., 2014)