I4

Type: Pharyngeal interneuron
In MoW:
Male Wiring Project: I4
In Wormbase: I4
Lineage: MS aaaapaa
Location: Pharynx posterior bulb
Description: The soma of I4 is located on the dorsal side of the terminal bulb commissure. A branch from each side runs within the terminal bulb commissure and continues anteriorly to the nerve ring in the subventral nerve cords.

On the ventral side of the nerve ring, these processes cross over to the other side. The right branch travels dorsally around the left half of the nerve ring and ends buried in pm1. The left branch travels dorsally around the right side of the ring and terminates at the level of the right subdorsal apex of the pharyngeal lumen (Albertson and Thomson, 1976)
Neurotransmitter/Neuropeptide:
- NLP-3; neuropeptide-like protein
- NLP-13; neuropeptide-like protein
(Nathoo et al., 2001)
Innexin expression:

No gap junctions predicted in the adult (Albertson and Thomson, 1976)
Receptor expression:
Function:
- Unknown or redundant (Avery and Thomas, 1997)


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I4 (MS aaaapaa) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of I4; dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).


Last revision: December 24, 2013
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