Type: Interneuron
In MoW: DVC
Male Wiring Project: DVC
In Wormbase: DVC
Lineage: C aapaa
Location: Dorsorectal ganglion
Description: Ring interneurons.
Neurotransmitter/ Neuropeptide:
-Glutamate
[N.B. DVA is cholinergic, while DVC is not]
(Pereira et al., 2015; Serrano-Saiz et al., 2013)
Innexin expression:
- INX-4
- INX-5
- INX-7
- INX-9
- INX-10
- INX-11
- INX-13
- INX-17 (early larva)
- INX-18
- UNC-7
- UNC-9
(Altun et al., 2009)
Receptor expression:
- GLR-1; glutamate receptor subunit
- SER-4; serotonin receptor, variably expressed (the neuron can be DVA instead)
- TRP-4; mechanosensitive TRPN channel
(Tsalik et al., 2003; Hart et al., 1995)
Function:
- It is suggested DVC may be a stretch receptor that functions in backward locomotion. Activation of DVC induces reversal through synapses onto AVA command interneurons and glutamatergic output from DVC is required for this backing (Ardiel & Rankin, 2015)