AVL

Type: Polymodal (interneuron, motor neuron)
In MoW: AVL
Male Wiring Project: AVL
In Wormbase: AVL
Lineage: AB prpappaap
Location: Ventral ganglion in head
Description: An excitatory motor neuron for enteric muscles as well as a ring and ventral cord interneuron, few synapses. In males, makes gap junctions with PDB, has a few synapses onto gonad and ventral body wall muscles (Jarrell et al., 2012)
Neurotransmitter/ Neuropeptide:
- GABA
(Eastman et al., 1999)
Innexin expression:
None yet reported, although described to have gap junctions in adult animals (MoW)
Receptor expression:
Function:
- Defecation. AVL and DVB are excitatory GABAergic motor neurons for the enteric muscles (Avery and Thomas, 1997; McIntire et al., 1993). Together with DVB, activates expulsion muscle contraction (E.p or EMC), also required for anterior body contraction (aBoc) step in defecation motor program (DMP).



Click image for closeup view Click pictures for higher resolution images


 
 

Click here for larger version
AVL (AB prpappaap) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of AVL; dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).

image