AIN

AINL, AINR

Type: Interneuron
In MoW: AIN
In WormWiring: AINL_h, AINR_h, AINL_m, AINR_m
In Wormbase: AIN, AINL, AINR
Lineage: AB alaaaalal, AB alaapaaar
Location: Lateral ganglia in the head
Description: Ring interneurons. The process of each AIN neuron enters the nerve ring subdorsally and after crossing the dorsal midline, runs round the nerve ring on the opposite side. After entering the ventral cord on the contralateral side, it ends within the ventral ganglion
Neurotransmitter/ Neuropeptide:
- Acetylcholine
- FLP-19; FMRFamide-like peptide
(Although earlier reports suggested AIN might be glutamatergic, more recent studies showed it is not)

(Pereira et al., 2015; Serrano-Saiz et al., 2013; Loer, 2010; Li and Kim, 2008; Lee et al., 1999)
Innexin expression:
- INX-4
- INX-8
- INX-17
- UNC-7
- UNC-9
(Altun et al., 2009)
Receptor expression: Unknown
Function: AIN is presynaptic to AFD, however, the significance of this connection is not yet clear

Click pictures for higher resolution images

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AINL (AB alaaaalal) development in the embryo. Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of AINL; dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).

Click here for larger version
AINR (AB alaapaaar) development in the embryo. Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of AINR (since last AINR ancestor has not yet gone through its final division, the black sphere seen at the end of this movie is still AB alaapaaa); dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).

Last revision: September 20, 2012