Type: Pharyngeal interneuron (also anterior sensory?)
In MoW:
Male Wiring Project: I3
In Wormbase: I3
Lineage: MS aaaaapaa
Location: Pharynx anterior bulb
Description: Anteriorly, I3 is inserted onto muscles pm1 and pm2 and terminates

anterior to the dorsal gland cell duct with a proprioceptive-like ending. Posterior process terminates on the dorsal side of the nerve ring (Albertson and Thomson, 1976)
Neurotransmitter/ Neuropeptide:
- Acetylcholine
- NLP-3; neuropeptide-like protein
(Pereira et al., 2015; Nathoo et al., 2001)
Innexin expression:
- INX-9
(Altun et al., 2009)
Receptor expression:
- GLR-7; glutamate receptor subunit
- GLR-8; glutamate receptor subunit
(Brockie et al., 2001)
- Unknown or redundant (Avery and Thomas, 1997)

Click image for closeup view Click pictures for higher resolution images


Click here for larger version
I3 (MS aaaaapaa) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of I3 (since last I3 ancestor has not yet gone through its final division, the black sphere seen at the end of this movie is still MS aaaaapa); dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).

Last revision: December 24, 2013